Imagine Doctor Who with an alcoholic sociopath Doctor and constant dark humor, in the style of a Western animated show that lampshades or subverts oodles of sci-fi, fantasy, pop culture and comedy tropes.
I recently binged the entire series up to date. Absolutely wonderful, with regular bits that get full, honest laughs out of me. Rick is equally terrifying, entertaining, awesome and a little endearing by turns - a conspicuously complex character for the context. The genre-savvy writing and brutal moral choices that Rick makes (or refuses to make) add some mild value to dissecting it. The half-improvised performances add a sense of spontaneity and chaos (i.e. natural feeling) to the pacing. The attention to detail in the animation and just general experimentation with the format add notable artistic value to the mix.
There's just a lot going for the show in general. While I think there's some weak episodes in season two, I'm generally very impressed by the series. And it's pretty easy to know if you're going to like it or not; the pilot episode doesn't go from 0 to 100, it starts at 100. Easy in. Check it out - I'm glad that I did.