There can’t be more than 12 different kinds of nucleobase without a significant rewrite of the WatsonCrick type of DNAage.
Assume each one is a pyrimidine (or isomeric to a pyrimidine) or is a purine (or isomeric to a purine).
With 12 different nucleobases and 2 nucleobases per codon, we could have as many as 144 different codes. That’s significantly more than the 64 we have IRL now, but it’s less than 700.
With 8 nucleobases and 3 bases per codon we’d have only 512 different codes.
With 4 nucleobases and 4 bases per codon we’d have only 256.
And with 2 and 9, only 512.
Posted January 22nd
Experiments have been accomplished that:
* had ribosomes and tRNAs and mRNAs that could translate codons made out of 6 kinds of nucleobases,
* had ribosomes and tRNAs and mRNAs that could translate codons that were four bases long,
* had ribosomes and tRNAs and mRNAs that could translate codons that were five bases long.
Posted February 11th